Gisadenafil besylate

• CAT Number: I010674
• CAS Number: 334827-98-4
• Molecular Formula: C29H39N7O8S2
• Molecular Weight: 677.79
• Purity: ≥95%
• Synonyms: benzenesulfonic acid;5-[2-ethoxy-5-(4-ethylpiperazin-1-yl)sulfonylpyridin-3-yl]-3-ethyl-2-(2-methoxyethyl)-6H-pyrazolo[4,3-d]pyrimidin-7-one
• IUPAC Name: benzenesulfonic acid;5-[2-ethoxy-5-(4-ethylpiperazin-1-yl)sulfonyl-3-pyridinyl]-3-ethyl-2-(2-methoxyethyl)-6H-pyrazolo[4,3-d]pyrimidin-7-one
• InChI: InChI=1S/C23H33N7O5S.C6H6O3S/c1-5-18-19-20(27-30(18)12-13-34-4)22(31)26-21(25-19)17-14-16(15-24-23(17)35-7-3)36(32,33)29-10-8-28(6-2)9-11-29;7-10(8,9)6-4-2-1-3-5-6/h14-15H,5-13H2,1-4H3,(H,25,26,31);1-5H,(H,7,8,9)
• InChIKey: STFRDYSZKVPPQF-UHFFFAOYSA-N
• SMILES: CCC1=C2C(=NN1CCOC)C(=O)NC(=N2)C3=C(N=CC(=C3)S(=O)(=O)N4CCN(CC4)CC)OCC.C1=CC=C(C=C1)S(=O)(=O)O

Gisadenafil besylate（Cat No.:I010674）is a selective phosphodiesterase type 5 (PDE5) inhibitor developed for the treatment of erectile dysfunction and related vascular conditions. By blocking PDE5, it enhances cyclic guanosine monophosphate (cGMP) signaling, promoting relaxation of smooth muscle in the corpus cavernosum and improving penile blood flow during sexual stimulation. Structurally related to sildenafil, gisadenafil offers potent efficacy with a favorable pharmacokinetic profile. The besylate salt improves stability and solubility for oral administration. Gisadenafil besylate remains primarily studied in clinical research as a therapeutic candidate for sexual health disorders.