Gelsevirine

• CAT Number: R013728
• CAS Number: 38990-03-3
• Molecular Formula: C21H24N2O3
• Molecular Weight: 352.43
• Purity: ≥95%
• Synonyms: (1R,2S,5S,6S,7S,8R,11S)-2-ethenyl-1′-methoxy-4-methylspiro[9-oxa-4-azatetracyclo[6.3.1.02,6.05,11]dodecane-7,3′-indole]-2′-one
• IUPAC Name: (1R,2S,5S,6S,7S,8R,11S)-2-ethenyl-1'-methoxy-4-methylspiro[9-oxa-4-azatetracyclo[6.3.1.02,6.05,11]dodecane-7,3'-indole]-2'-one
• InChI: InChI=1S/C21H24N2O3/c1-4-20-11-22(2)17-12-10-26-16(9-14(12)20)21(18(17)20)13-7-5-6-8-15(13)23(25-3)19(21)24/h4-8,12,14,16-18H,1,9-11H2,2-3H3/t12-,14+,16+,17+,18-,20-,21-/m0/s1
• InChIKey: SSSCMFCWHWCCEH-MTYPYGCKSA-N
• SMILES: CN1C[C@]2([C@@H]3C[C@@H]4[C@]5([C@H]2[C@H]1[C@H]3CO4)C6=CC=CC=C6N(C5=O)OC)C=C

Gelsevirine（Cat No.:R013728）is an indole alkaloid isolated from Gelsemium elegans, a plant known for its use in traditional medicine and its potent bioactive compounds. Structurally, gelsevirine features a complex indole-based framework typical of Gelsemium alkaloids. It has been studied for its analgesic, anti-inflammatory, and neuroactive properties, with research suggesting potential modulation of central nervous system signaling. However, like other Gelsemium alkaloids, gelsevirine exhibits notable toxicity, requiring careful handling in research. It remains a valuable molecule in phytochemistry and pharmacology for exploring therapeutic mechanisms and alkaloid-based drug discovery.