For research use only. Not for therapeutic Use.
GAK inhibitor 49（Cat No.:I014989）is a selective small-molecule compound targeting cyclin G-associated kinase (GAK), a serine/threonine kinase involved in clathrin-mediated endocytosis, cell cycle progression, and signaling regulation. By inhibiting GAK, this compound disrupts receptor trafficking and cellular proliferation pathways, making it a valuable probe in cancer biology and virology. GAK inhibitor 49 has been applied in studies investigating viral entry mechanisms, including those of hepatitis C and influenza, as well as tumor growth regulation. Its selectivity provides a useful platform for therapeutic exploration and mechanistic research.
| CAS Number | 319492-82-5 |
| Synonyms | 6,7-dimethoxy-N-(3,4,5-trimethoxyphenyl)quinolin-4-amine |
| Molecular Formula | C20H22N2O5 |
| Purity | ≥95% |
| IUPAC Name | 6,7-dimethoxy-N-(3,4,5-trimethoxyphenyl)quinolin-4-amine |
| InChI | InChI=1S/C20H22N2O5/c1-23-16-10-13-14(6-7-21-15(13)11-17(16)24-2)22-12-8-18(25-3)20(27-5)19(9-12)26-4/h6-11H,1-5H3,(H,21,22) |
| InChIKey | VYPGLYMWNDRFGZ-UHFFFAOYSA-N |
| SMILES | COC1=CC(=CC(=C1OC)OC)NC2=C3C=C(C(=CC3=NC=C2)OC)OC |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
