Gabapentin-d4

• CAT Number: R060057
• CAS Number: 1185039-20-6
• Molecular Formula: C9H13D4NO2
• Molecular Weight: 175.26
• Purity: ≥95%
• Synonyms: 2-[1-[amino(dideuterio)methyl]cyclohexyl]-2,2-dideuterioacetic acid
• InChI: InChI=1S/C9H17NO2/c10-7-9(6-8(11)12)4-2-1-3-5-9/h1-7,10H2,(H,11,12)/i6D2,7D2
• InChIKey: UGJMXCAKCUNAIE-KXGHAPEVSA-N
• SMILES: [2H]C([2H])(C(=O)O)C1(CCCCC1)C([2H])([2H])N

Gabapentin-d4（Cat No.:R060057）is a deuterium-labeled analog of gabapentin, containing four deuterium atoms, used primarily as an internal standard in LC-MS/MS assays for accurate quantification of gabapentin levels in biological samples. Gabapentin itself is a structural analog of GABA, prescribed for epilepsy, neuropathic pain, and restless leg syndrome. Although it does not directly interact with GABA receptors, it binds to the α2δ subunit of voltage-gated calcium channels, reducing excitatory neurotransmitter release. Gabapentin-d4 mirrors the pharmacokinetic and chemical properties of gabapentin, making it ideal for bioanalytical and pharmacokinetic research applications.