For research use only. Not for therapeutic Use.
FzM1.8（Cat No.:I018165）is a selective small-molecule inhibitor targeting the Frizzled (Fz) receptor family, key components of the Wnt signaling pathway. By blocking Wnt–Frizzled interactions, FzM1.8 interferes with downstream β-catenin–mediated transcription, which regulates cell proliferation, differentiation, and survival. Dysregulation of Wnt/Frizzled signaling is strongly implicated in cancer progression, stem cell maintenance, and tissue regeneration. Research with FzM1.8 provides valuable insights into developmental biology, tumorigenesis, and regenerative medicine. Its ability to selectively probe Wnt–Frizzled signaling makes it an important tool in oncology and molecular signaling studies.
| CAS Number | 2204290-85-5 |
| Synonyms | 3-hydroxy-5-(naphthalen-2-ylcarbamoylamino)benzoic acid |
| Molecular Formula | C18H14N2O4 |
| Purity | ≥95% |
| IUPAC Name | 3-hydroxy-5-(naphthalen-2-ylcarbamoylamino)benzoic acid |
| InChI | InChI=1S/C18H14N2O4/c21-16-9-13(17(22)23)8-15(10-16)20-18(24)19-14-6-5-11-3-1-2-4-12(11)7-14/h1-10,21H,(H,22,23)(H2,19,20,24) |
| InChIKey | XGNNCRZDDAJBFU-UHFFFAOYSA-N |
| SMILES | C1=CC=C2C=C(C=CC2=C1)NC(=O)NC3=CC(=CC(=C3)C(=O)O)O |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
