FXR antagonist 1

• CAT Number: I042816
• CAS Number: 2295804-68-9
• Molecular Formula: C36H59NO5
• Molecular Weight: 585.86
• Purity: ≥95%
• Synonyms: 2-[[(1S,3aS,5aR,5bR,9R,11aR)-9-butanoyloxy-5a,5b,8,8,11a-pentamethyl-1-propan-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysene-3a-carbonyl]amino]acetic acid
• IUPAC Name: 2-[[(1S,3aS,5aR,5bR,7aR,9R,11aR,11bR,13aR,13bR)-9-butanoyloxy-5a,5b,8,8,11a-pentamethyl-1-propan-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysene-3a-carbonyl]amino]acetic acid
• InChI: InChI=1S/C36H59NO5/c1-9-10-29(40)42-27-15-16-33(6)25(32(27,4)5)14-17-35(8)26(33)12-11-24-30-23(22(2)3)13-18-36(30,20-19-34(24,35)7)31(41)37-21-28(38)39/h22-27,30H,9-21H2,1-8H3,(H,37,41)(H,38,39)/t23-,24+,25-,26+,27+,30+,33-,34+,35+,36-/m0/s1
• InChIKey: CLKCLHBPLVDIOB-VCXUAKCGSA-N
• SMILES: CCCC(=O)O[C@@H]1CC[C@@]2([C@H]3CC[C@@H]4[C@H]5[C@@H](CC[C@@]5(CC[C@]4([C@@]3(CC[C@H]2C1(C)C)C)C)C(=O)NCC(=O)O)C(C)C)C

FXR Antagonist 1（Cat No.:I042816）is a small molecule compound designed to selectively inhibit the farnesoid X receptor (FXR), a nuclear receptor involved in regulating bile acid synthesis, metabolism, and liver function. FXR plays a key role in the regulation of glucose and lipid metabolism, as well as inflammation. By blocking FXR activity, FXR Antagonist 1 is being investigated for its potential therapeutic applications in metabolic diseases such as non-alcoholic fatty liver disease (NAFLD), obesity, and type 2 diabetes. Research is ongoing to evaluate its ability to modulate these pathways and improve metabolic health.