Furegrelate sodium

• CAT Number: I011811
• CAS Number: 85666-17-7
• Molecular Formula: C15H10NNaO3
• Molecular Weight: 275.23
• Purity: ≥95%
• Synonyms: sodium;5-(pyridin-3-ylmethyl)-1-benzofuran-2-carboxylate
• InChI: InChI=1S/C15H11NO3.Na/c17-15(18)14-8-12-7-10(3-4-13(12)19-14)6-11-2-1-5-16-9-11;/h1-5,7-9H,6H2,(H,17,18);/q;+1/p-1
• InChIKey: XBTIPIZROJAKOJ-UHFFFAOYSA-M
• SMILES: C1=CC(=CN=C1)CC2=CC3=C(C=C2)OC(=C3)C(=O)[O-].[Na+]

Furegrelate sodium(CAT: I011811) is a potent, selective inhibitor of thromboxane A₂ synthase, the enzyme responsible for converting prostaglandin H₂ to thromboxane A₂ (TXA₂). By blocking TXA₂ production, Furegrelate effectively reduces platelet aggregation and vasoconstriction, making it a valuable pharmacological tool in cardiovascular and thrombosis research. It has been widely studied for its potential in preventing platelet-driven disorders, such as myocardial ischemia, stroke, and atherosclerosis. In experimental settings, Furegrelate sodium provides insight into prostanoid signaling pathways and the role of thromboxane in vascular homeostasis. Its high selectivity makes it a preferred compound for dissecting thromboxane-mediated mechanisms in vitro and in vivo.