FPH1

For research use only. Not for therapeutic Use.

  • CAT Number: R060724
  • CAS Number: 708219-39-0
  • Molecular Formula: C16H15ClF2N2O3S
  • Molecular Weight: 388.82
  • Purity: ≥95%
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FPH1(Cat No.:R060724)is a small-molecule compound known for promoting the proliferation and function of human hepatocytes. Identified through high-throughput screening, FPH1 enhances the maturation and metabolic activity of primary human liver cells in vitro, supporting applications in liver disease modeling, toxicity testing, and regenerative medicine. It works by modulating signaling pathways involved in hepatocyte differentiation and survival, including those related to FOXA2 and HNF4α. FPH1 is commonly used alongside other hepatocyte proliferation enhancers to maintain liver-specific functions during extended cell culture, making it valuable for drug metabolism and pharmacokinetics (DMPK) research.


CAS Number 708219-39-0
Synonyms

2-(5-chloro-2-methyl-N-methylsulfonylanilino)-N-(2,6-difluorophenyl)acetamide

Molecular Formula C16H15ClF2N2O3S
Purity ≥95%
IUPAC Name 2-(5-chloro-2-methyl-N-methylsulfonylanilino)-N-(2,6-difluorophenyl)acetamide
InChI InChI=1S/C16H15ClF2N2O3S/c1-10-6-7-11(17)8-14(10)21(25(2,23)24)9-15(22)20-16-12(18)4-3-5-13(16)19/h3-8H,9H2,1-2H3,(H,20,22)
InChIKey WAOBCCBUTHNTFO-UHFFFAOYSA-N
SMILES CC1=C(C=C(C=C1)Cl)N(CC(=O)NC2=C(C=CC=C2F)F)S(=O)(=O)C
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