For research use only. Not for therapeutic Use.
Fmoc-Thr(tBu)-OH(CAT: L014979) is a protected form of the amino acid threonine, widely used in solid-phase peptide synthesis (SPPS). It contains an Fmoc (9-fluorenylmethyloxycarbonyl) group protecting the α-amino group and a tert-butyl (tBu) group shielding the side-chain hydroxyl group. This dual protection allows for selective deprotection steps during peptide elongation, preventing unwanted side reactions. With the molecular formula C₂₄H₂₇NO₅, it appears as a white to off-white crystalline powder and is soluble in common organic solvents like DMF and DCM. Fmoc-Thr(tBu)-OH ensures high efficiency and purity in automated or manual peptide synthesis, making it essential in pharmaceutical and biochemical research.
| CAS Number | 71989-35-0 |
| Molecular Formula | C23H27NO5 |
| Purity | ≥95% |
| IUPAC Name | (2S,3R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-[(2-methylpropan-2-yl)oxy]butanoic acid |
| InChI | InChI=1S/C23H27NO5/c1-14(29-23(2,3)4)20(21(25)26)24-22(27)28-13-19-17-11-7-5-9-15(17)16-10-6-8-12-18(16)19/h5-12,14,19-20H,13H2,1-4H3,(H,24,27)(H,25,26)/t14-,20+/m1/s1 |
| InChIKey | LZOLWEQBVPVDPR-VLIAUNLRSA-N |
| SMILES | C[C@H]([C@@H](C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13)OC(C)(C)C |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
