For research use only. Not for therapeutic Use.
Fmoc-PEG1-CH2CH2-NHS ester(CAT: I016389) is a bifunctional PEGylated reagent designed for peptide synthesis and bioconjugation. It features an Fmoc-protected amine group, a short PEG1 spacer with an ethylene linker, and an N-hydroxysuccinimide (NHS) ester. The Fmoc group provides temporary protection for controlled solid-phase peptide synthesis or stepwise modifications, while the NHS ester reacts efficiently with primary amines to form stable amide bonds. The PEG1 spacer introduces flexibility, hydrophilicity, and reduced steric hindrance in conjugation. This reagent is particularly valuable for linking biomolecules, preparing modified peptides, or introducing PEG units into complex molecular frameworks for research and drug development applications.
CAS Number | 1807521-05-6 |
Synonyms | (2,5-dioxopyrrolidin-1-yl) 3-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethoxy]propanoate |
Molecular Formula | C24H24N2O7 |
Purity | ≥95% |
IUPAC Name | (2,5-dioxopyrrolidin-1-yl) 3-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethoxy]propanoate |
InChI | InChI=1S/C24H24N2O7/c27-21-9-10-22(28)26(21)33-23(29)11-13-31-14-12-25-24(30)32-15-20-18-7-3-1-5-16(18)17-6-2-4-8-19(17)20/h1-8,20H,9-15H2,(H,25,30) |
InChIKey | BGPXUJXGIVJFGP-UHFFFAOYSA-N |
SMILES | C1CC(=O)N(C1=O)OC(=O)CCOCCNC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24 |
Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |