Fmoc-PEG1-CH2CH2-NHS ester

For research use only. Not for therapeutic Use.

  • CAT Number: I016389
  • CAS Number: 1807521-05-6
  • Molecular Formula: C24H24N2O7
  • Molecular Weight: 452.46
  • Purity: ≥95%
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Fmoc-PEG1-CH2CH2-NHS ester(CAT: I016389) is a bifunctional PEGylated reagent designed for peptide synthesis and bioconjugation. It features an Fmoc-protected amine group, a short PEG1 spacer with an ethylene linker, and an N-hydroxysuccinimide (NHS) ester. The Fmoc group provides temporary protection for controlled solid-phase peptide synthesis or stepwise modifications, while the NHS ester reacts efficiently with primary amines to form stable amide bonds. The PEG1 spacer introduces flexibility, hydrophilicity, and reduced steric hindrance in conjugation. This reagent is particularly valuable for linking biomolecules, preparing modified peptides, or introducing PEG units into complex molecular frameworks for research and drug development applications.


CAS Number 1807521-05-6
Synonyms

(2,5-dioxopyrrolidin-1-yl) 3-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethoxy]propanoate

Molecular Formula C24H24N2O7
Purity ≥95%
IUPAC Name (2,5-dioxopyrrolidin-1-yl) 3-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethoxy]propanoate
InChI InChI=1S/C24H24N2O7/c27-21-9-10-22(28)26(21)33-23(29)11-13-31-14-12-25-24(30)32-15-20-18-7-3-1-5-16(18)17-6-2-4-8-19(17)20/h1-8,20H,9-15H2,(H,25,30)
InChIKey BGPXUJXGIVJFGP-UHFFFAOYSA-N
SMILES C1CC(=O)N(C1=O)OC(=O)CCOCCNC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24
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