Fmoc-NH-PEG4-alcohol

• CAT Number: I016245
• CAS Number: 868594-41-6
• Molecular Formula: C23H29NO6
• Molecular Weight: 415.48
• Purity: ≥95%
• Synonyms: 9H-fluoren-9-ylmethyl N-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethyl]carbamate
• InChI: InChI=1S/C23H29NO6/c25-10-12-28-14-16-29-15-13-27-11-9-24-23(26)30-17-22-20-7-3-1-5-18(20)19-6-2-4-8-21(19)22/h1-8,22,25H,9-17H2,(H,24,26)
• InChIKey: UZWYVXFJNFHOMM-UHFFFAOYSA-N
• SMILES: C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NCCOCCOCCOCCO

Fmoc-NH-PEG4-alcohol(CAT: I016245) is a heterobifunctional PEG linker featuring an Fmoc-protected amine at one end and a primary alcohol at the other, connected via a four-unit polyethylene glycol (PEG4) spacer. The Fmoc group provides temporary protection, enabling controlled incorporation of the amine into solid-phase peptide synthesis (SPPS) or other synthetic workflows. The terminal alcohol serves as a versatile reactive site for further derivatization, such as oxidation or esterification. The PEG4 spacer enhances solubility, reduces steric hindrance, and improves biocompatibility, making this reagent valuable in inhibitor development, peptide–drug conjugates, and bioconjugation strategies for cancer, immunology, and metabolic disease research.