Fmoc-N-PEG24-acid

• CAT Number: I016320
• CAS Number: 2170484-59-8
• Molecular Formula: C66H113NO28
• Molecular Weight: 1368.59
• Purity: ≥95%
• Synonyms: 3-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
• InChI: InChI=1S/C66H113NO28/c68-65(69)9-11-71-13-15-73-17-19-75-21-23-77-25-27-79-29-31-81-33-35-83-37-39-85-41-43-87-45-47-89-49-51-91-53-55-93-57-58-94-56-54-92-52-50-90-48-46-88-44-42-86-40-38-84-36-34-82-32-30-80-28-26-78-24-22-76-20-18-74-16-14-72-12-10-67-66(70)95-59-64-62-7-3-1-5-60(62)61-6-2-4-8-63(61)64/h1-8,64H,9-59H2,(H,67,70)(H,68,69)
• InChIKey: NFOMZHGRFWXDGH-UHFFFAOYSA-N
• SMILES: C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)O

Fmoc-N-PEG24-acid(CAT: I016320) is a heterobifunctional polyethylene glycol (PEG) derivative featuring an Fmoc-protected amine on one terminus and a free carboxylic acid on the other. The PEG24 chain provides an extended, flexible, and highly hydrophilic spacer that enhances solubility, reduces steric hindrance, and improves biocompatibility. The Fmoc group protects the terminal amine, allowing controlled deprotection under mild basic conditions (typically piperidine) for sequential conjugation steps. Meanwhile, the terminal carboxyl group enables coupling to amines or other nucleophiles through amide or ester bond formation. This reagent is particularly useful in solid-phase peptide synthesis, bioconjugation, drug delivery, and polymer modification where long PEG spacers are required.