Fmoc-L-Asn(beta-D-GlcNAc(Ac)3)-OH

• CAT Number: M117128
• CAS Number: 131287-39-3
• Molecular Formula: C33H37N3O13
• Molecular Weight: 683.66
• Purity: ≥95%
• Synonyms: (2S)-4-[[(2R,3R,4R,5S,6R)-3-acetamido-4,5-diacetyloxy-6-(acetyloxymethyl)oxan-2-yl]amino]-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-oxobutanoic acid
• InChI: InChI=1S/C33H37N3O13/c1-16(37)34-28-30(48-19(4)40)29(47-18(3)39)26(15-45-17(2)38)49-31(28)36-27(41)13-25(32(42)43)35-33(44)46-14-24-22-11-7-5-9-20(22)21-10-6-8-12-23(21)24/h5-12,24-26,28-31H,13-15H2,1-4H3,(H,34,37)(H,35,44)(H,36,41)(H,42,43)/t25-,26+,28+,29+,30+,31+/m0/s1
• InChIKey: QOACISSHGAAMLK-MJCYOTSPSA-N
• SMILES: CC(=O)N[C@@H]1[C@H]([C@@H]([C@H](O[C@H]1NC(=O)C[C@@H](C(=O)O)NC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24)COC(=O)C)OC(=O)C)OC(=O)C

Fmoc-L-Asn(β-D-GlcNAc(Ac)₃)-OH（Cat No.:M117128）is a protected glycosylated amino acid used in solid-phase peptide synthesis (SPPS) to incorporate N-linked glycosylation motifs into peptides. It features an Fmoc group for N-terminal protection and an acetylated β-D-N-acetylglucosamine (GlcNAc) moiety attached to the side chain of L-asparagine. The acetyl groups protect hydroxyl functionalities during synthesis, ensuring stability and minimizing side reactions. This building block enables the preparation of glycopeptides for studying protein–carbohydrate interactions, glycoprotein structure–function relationships, and immune recognition, as well as for developing glycopeptide-based therapeutics and biomaterials in advanced biomedical and chemical research.