For research use only. Not for therapeutic Use.
Fmoc-D-Lys(N₃)-OH (Cat No.: I042597) is a protected amino acid derivative used in solid-phase peptide synthesis (SPPS). It features a D-lysine backbone with an azide (-N₃) functional group on the side chain and an Fmoc (fluorenylmethyloxycarbonyl) group protecting the α-amino group. The azide moiety enables bioorthogonal conjugation via click chemistry, allowing selective attachment of probes, drugs, or labels. Fmoc-D-Lys(N₃)-OH is ideal for introducing site-specific modifications in peptides, facilitating applications in chemical biology, drug delivery, and the development of multifunctional peptide-based tools.
| CAS Number | 1198791-53-5 |
| Synonyms | (2R)-6-azido-2-(9H-fluoren-9-ylmethoxycarbonylamino)hexanoic acid |
| Molecular Formula | C21H22N4O4 |
| Purity | ≥95% |
| InChI | InChI=1S/C21H22N4O4/c22-25-23-12-6-5-11-19(20(26)27)24-21(28)29-13-18-16-9-3-1-7-14(16)15-8-2-4-10-17(15)18/h1-4,7-10,18-19H,5-6,11-13H2,(H,24,28)(H,26,27)/t19-/m1/s1 |
| InChIKey | PJRFTUILPGJJIO-LJQANCHMSA-N |
| SMILES | C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NC(CCCCN=[N+]=[N-])C(=O)O |
| Reference | [1]. Sminia, et al. Azide- and alkyne-functionalized α- and β3-amino acids. Synlett |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
