For research use only. Not for therapeutic Use.
Fmoc-aminooxy-PEG2-NH2 (Cat No.: I045432) is a heterobifunctional linker featuring an Fmoc-protected aminooxy group at one end and a free primary amine at the other, connected by a PEG2 spacer (two ethylene glycol units). The aminooxy group reacts selectively with carbonyl-containing compounds (e.g., aldehydes, ketones) to form stable oxime linkages, while the amine enables further conjugation to activated esters or carboxylic acids. The PEG2 spacer enhances solubility and reduces steric hindrance, making this reagent valuable for bioconjugation, peptide modification, and chemical biology research applications.
| CAS Number | 190249-87-7 |
| Synonyms | 9H-fluoren-9-ylmethyl N-[2-(2-aminooxyethoxy)ethoxy]carbamate |
| Molecular Formula | C19H22N2O5 |
| Purity | ≥95% |
| InChI | InChI=1S/C19H22N2O5/c20-25-11-9-23-10-12-26-21-19(22)24-13-18-16-7-3-1-5-14(16)15-6-2-4-8-17(15)18/h1-8,18H,9-13,20H2,(H,21,22) |
| InChIKey | PJENKAHPGFOITB-UHFFFAOYSA-N |
| SMILES | C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NOCCOCCON |
| Reference | [1]. Siekmann J, et, al. Materials and methods for conjugating a water soluble fatty acid derivative to a protein. US20120190096A1. |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
