For research use only. Not for therapeutic Use.
Fluocortolone(CAT: R047640) is a synthetic corticosteroid with strong anti-inflammatory, anti-allergic, and immunosuppressive properties. Structurally related to prednisolone, it is commonly used in research focused on glucocorticoid receptor signaling, inflammatory response modulation, and skin or mucosal inflammation. Fluocortolone exerts its effects by inhibiting the synthesis of pro-inflammatory mediators such as prostaglandins and cytokines, making it valuable for studying conditions like dermatitis, colitis, and other immune-related disorders. Its potent topical and systemic activities also support investigations into corticosteroid pharmacodynamics and tissue-specific effects.
| CAS Number | 152-97-6 |
| Synonyms | (6S,8S,9S,10R,11S,13S,14S,16R,17S)-6-fluoro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-one |
| Molecular Formula | C22H29FO4 |
| Purity | ≥95% |
| IUPAC Name | (6S,8S,9S,10R,11S,13S,14S,16R,17S)-6-fluoro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-one |
| InChI | InChI=1S/C22H29FO4/c1-11-6-14-13-8-16(23)15-7-12(25)4-5-21(15,2)20(13)17(26)9-22(14,3)19(11)18(27)10-24/h4-5,7,11,13-14,16-17,19-20,24,26H,6,8-10H2,1-3H3/t11-,13+,14+,16+,17+,19-,20-,21+,22+/m1/s1 |
| InChIKey | GAKMQHDJQHZUTJ-ULHLPKEOSA-N |
| SMILES | CC1CC2C3CC(C4=CC(=O)C=CC4(C3C(CC2(C1C(=O)CO)C)O)C)F |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
