For research use only. Not for therapeutic Use.
FLT3-IN-6（Cat No.:I018996）is a selective small-molecule inhibitor of FMS-like tyrosine kinase 3 (FLT3), a receptor tyrosine kinase critically implicated in acute myeloid leukemia (AML). By blocking FLT3 signaling, it suppresses downstream pathways such as PI3K/AKT and MAPK that drive leukemic cell proliferation and survival. FLT3-IN-6 is widely used in preclinical oncology studies to evaluate targeted therapy strategies, drug resistance mechanisms, and kinase inhibitor selectivity. This compound provides researchers with a valuable tool for investigating hematologic malignancies and advancing therapeutic development for FLT3-driven cancers.
| CAS Number | 2377141-31-4 |
| Synonyms | N-[5-(1,3-benzodioxol-5-yl)-1H-pyrazol-3-yl]-4-[(1-methylpiperidin-4-yl)amino]benzamide |
| Molecular Formula | C23H25N5O3 |
| Purity | ≥95% |
| IUPAC Name | N-[5-(1,3-benzodioxol-5-yl)-1H-pyrazol-3-yl]-4-[(1-methylpiperidin-4-yl)amino]benzamide |
| InChI | InChI=1S/C23H25N5O3/c1-28-10-8-18(9-11-28)24-17-5-2-15(3-6-17)23(29)25-22-13-19(26-27-22)16-4-7-20-21(12-16)31-14-30-20/h2-7,12-13,18,24H,8-11,14H2,1H3,(H2,25,26,27,29) |
| InChIKey | OKFAZZUSWJWRJN-UHFFFAOYSA-N |
| SMILES | CN1CCC(CC1)NC2=CC=C(C=C2)C(=O)NC3=NNC(=C3)C4=CC5=C(C=C4)OCO5 |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
