Finerenone - CAS 1050477-31-0
Finerenone(CAT: I006795), also known as BAY94-8862, is a non-steroidal antimineralocorticoid that is in phase III clinical trials for the treatment of chronic heart failure. It has a less relative affinity to other steroid hormone receptors than currently available antimineralocorticoids such as eplerenone and spironolactone, which should result in fewer adverse effects like gynecomastia. This product is used for medical research and development and other scientific research purposes.
Catalog Number: I006795
CAS Number: 1050477-31-0
PubChem Substance ID:355168412
Molecular Formula: C21H22N4O3
Molecular Weight:378.432
Purity: ≥95%
* For research use only. Not for human or veterinary use.
Synonym
| Synonyms | BAY94-8862; BAY 94-8862; BAY-94-8862; BAY948862; BAY 948862; BAY-948862; Finerenone;(4S)-4-(4-Cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxamide |
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Property
| Molecular Formula: | C21H22N4O3 |
|---|---|
| Molecular Weight | 378.432 |
| Solubility | Soluble in DMSO, not in water |
| Purity | ≥95% |
| Storage | 0 - 4°C for short term or -20 °C for long term |
Computed Descriptor
| IUPAC Name | (4S)-4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxamide |
|---|---|
| InChI | InChI=1S/C21H22N4O3/c1-5-28-21-18-17(14-7-6-13(9-22)8-15(14)27-4)16(20(23)26)12(3)25-19(18)11(2)10-24-21/h6-8,10,17,25H,5H2,1-4H3,(H2,23,26)/t17-/m1/s1 |
| InChIKey | BTBHLEZXCOBLCY-QGZVFWFLSA-N |
| SMILES | CCOC1=NC=C(C2=C1C(C(=C(N2)C)C(=O)N)C3=C(C=C(C=C3)C#N)OC)C |