Finerenone

  • CAT Number: I006795
  • CAS Number: 1050477-31-0
  • Molecular Formula: C21H22N4O3
  • Molecular Weight: 378.43
  • Purity: 98%
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Finerenone(Cat No.:I006795)is a non-steroidal mineralocorticoid receptor antagonist (MRA) used to treat chronic kidney disease (CKD) in patients with type 2 diabetes. By selectively blocking the mineralocorticoid receptor, finerenone reduces inflammation and fibrosis in the kidneys and heart, offering protective effects against CKD progression and cardiovascular complications. Unlike traditional MRAs, it has a lower risk of causing hyperkalemia. Finerenone provides an important therapeutic option for improving kidney function and reducing cardiovascular risk in diabetic patients with CKD, complementing standard treatments like ACE inhibitors or ARBs.


Catalog Number I006795
CAS Number 1050477-31-0
Synonyms

BAY94-8862; BAY 94-8862; BAY-94-8862; BAY948862; BAY 948862; BAY-948862; Finerenone;(4S)-4-(4-Cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxamide

Molecular Formula C21H22N4O3
Purity 98%
Target Mineralocorticoid receptor
Target Protein

P08235

Solubility Soluble in DMSO, not in water
Appearance Solid
Storage Dry, dark and at 2 - 8 °C for six months or -20°C for two years.
IUPAC Name (4S)-4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxamide
InChI InChI=1S/C21H22N4O3/c1-5-28-21-18-17(14-7-6-13(9-22)8-15(14)27-4)16(20(23)26)12(3)25-19(18)11(2)10-24-21/h6-8,10,17,25H,5H2,1-4H3,(H2,23,26)/t17-/m1/s1
InChIKey BTBHLEZXCOBLCY-QGZVFWFLSA-N
SMILES CCOC1=NC=C(C2=C1[C@@H](C(=C(N2)C)C(=O)N)C3=C(C=C(C=C3)C#N)OC)C

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