Fidaxomicin- CAS 873857-62-6

CAS No.: 873857-62-6

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Fidaxomicin,873857-62-6
Product Details
For research use only. Not Intended for Therapeutic Use!
Cat No:A000989
Synonyms:

OPT-80, PAR-101

Molecular Formula:

C52H74Cl2O18

Molecular Weight:1058.04
Description: Fidaxomicin(CAS 873857-62-6), a macrocyclic antibiotic, has a narrow spectrum of activity against gram-positive anaerobes and is bactericidal against C. difficile.  Fidaxomicin inhibits bacterial transcription by binding to RNA polymerase, a large enzyme that consists of five subunits that comprise its core catalytic enzyme (α2 ββ/' ω) and a separate sigma (σ) subunit responsible for promoter recognition.
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Fidaxomicin(CAS 873857-62-6), a macrocyclic antibiotic, has a narrow spectrum of activity against gram-positive anaerobes and is bactericidal against C. difficile. 



Fidaxomicin inhibits bacterial transcription by binding to RNA polymerase, a large enzyme that consists of five subunits that comprise its core catalytic enzyme (α2 ββ/' ω) and a separate sigma (σ) subunit responsible for promoter recognition. Fidaxomicin has no activity against gram-negative bacteria. Fidaxomicin has minimal activity against Bacteroides species, which may be advantageous in maintaining colonization resistance and protecting the gastrointestinal tract from colonization by C. difficile. 

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