FHT-1204

• CAT Number: I044026
• CAS Number: 2468048-24-8
• Molecular Formula: C24H23N5O5S2
• Molecular Weight: 525.60
• Purity: ≥95%
• Synonyms: N-[(2S)-3-methoxy-1-oxo-1-[[4-(3-pyridin-4-ylphenyl)-1,3-thiazol-2-yl]amino]propan-2-yl]-1-methylsulfonylpyrrole-3-carboxamide
• InChI: InChI=1S/C24H23N5O5S2/c1-34-14-20(26-22(30)19-8-11-29(13-19)36(2,32)33)23(31)28-24-27-21(15-35-24)18-5-3-4-17(12-18)16-6-9-25-10-7-16/h3-13,15,20H,14H2,1-2H3,(H,26,30)(H,27,28,31)/t20-/m0/s1
• InChIKey: AXMLAOCXALIIRY-FQEVSTJZSA-N
• SMILES: COC[C@@H](C(=O)NC1=NC(=CS1)C2=CC=CC(=C2)C3=CC=NC=C3)NC(=O)C4=CN(C=C4)S(=O)(=O)C

FHT-1204（Cat No.:I044026）is a selective inhibitor of bromodomain-containing protein 4 (BRD4), a member of the BET (bromodomain and extraterminal domain) family involved in regulating gene transcription through chromatin remodeling. By targeting BRD4, FHT-1204 disrupts the interaction between acetylated histones and transcriptional machinery, thereby downregulating expression of oncogenes such as MYC. This compound is particularly useful in cancer research, especially for studying hematologic malignancies and solid tumors. FHT-1204 also shows potential in inflammatory and epigenetic research, making it a powerful tool for investigating transcriptional control mechanisms in disease contexts.