FHT-1015

• CAT Number: I044027
• CAS Number: 2368903-18-6
• Molecular Formula: C25H25N5O4S3
• Molecular Weight: 555.69
• Purity: ≥95%
• Synonyms: N-[(2S)-4-methylsulfanyl-1-oxo-1-[[4-(3-pyridin-4-ylphenyl)-1,3-thiazol-2-yl]amino]butan-2-yl]-1-methylsulfonylpyrrole-3-carboxamide
• InChI: InChI=1S/C25H25N5O4S3/c1-35-13-9-21(27-23(31)20-8-12-30(15-20)37(2,33)34)24(32)29-25-28-22(16-36-25)19-5-3-4-18(14-19)17-6-10-26-11-7-17/h3-8,10-12,14-16,21H,9,13H2,1-2H3,(H,27,31)(H,28,29,32)/t21-/m0/s1
• InChIKey: FAYSHZVDWADZMD-NRFANRHFSA-N
• SMILES: CSCC[C@@H](C(=O)NC1=NC(=CS1)C2=CC=CC(=C2)C3=CC=NC=C3)NC(=O)C4=CN(C=C4)S(=O)(=O)C

FHT-1015（Cat No.:I044027）is a highly selective inhibitor of histone deacetylase 6 (HDAC6), an enzyme primarily involved in the deacetylation of non-histone proteins such as α-tubulin and HSP90. By targeting HDAC6, FHT-1015 modulates protein degradation, cell motility, and stress response pathways without broadly affecting gene transcription. This specificity makes it a valuable tool in studying neurodegenerative disorders, cancer, and inflammatory diseases. FHT-1015 has shown promise in promoting acetylation-related cellular effects while minimizing toxicity associated with pan-HDAC inhibition, offering a targeted approach for dissecting HDAC6-driven mechanisms in various pathological contexts.