FF-10101

• CAT Number: I027438
• CAS Number: 1472797-69-5
• Molecular Formula: C29H38N8O2
• Molecular Weight: 530.66
• Purity: ≥95%
• Storage: 3 years -20°C powder
• SMILES: CCCNC1=NC(=NC=C1C#CCCCNC(=O)C(C)N(C)C(=O)C=CCN(C)C)NC2=CC=C(C=C2)C#N

FF-10101 is a novel irreversible FLT3 inhibitor with ic50 of 0.20 nM and 0.16 nM for FLT3 (WT) and FLT3(D835Y), respectively.

Reference

[1] Yamaura T,et al.Blood. 2018 25;131(4):426-438.