Fesoterodine L-mandelate

• CAT Number: I015564
• CAS Number: 1206695-46-6
• Molecular Formula: C34H45NO6
• Molecular Weight: 563.72
• Purity: ≥95%
• Synonyms: [2-[(1R)-3-[di(propan-2-yl)amino]-1-phenylpropyl]-4-(hydroxymethyl)phenyl] 2-methylpropanoate;(2S)-2-hydroxy-2-phenylacetic acid
• InChI: InChI=1S/C26H37NO3.C8H8O3/c1-18(2)26(29)30-25-13-12-21(17-28)16-24(25)23(22-10-8-7-9-11-22)14-15-27(19(3)4)20(5)6;9-7(8(10)11)6-4-2-1-3-5-6/h7-13,16,18-20,23,28H,14-15,17H2,1-6H3;1-5,7,9H,(H,10,11)/t23-;7-/m10/s1
• InChIKey: BUMCIEARGQDQNL-SXTNJFIWSA-N
• SMILES: CC(C)C(=O)OC1=C(C=C(C=C1)CO)[C@H](CCN(C(C)C)C(C)C)C2=CC=CC=C2.C1=CC=C(C=C1)[C@@H](C(=O)O)O

Fesoterodine L-mandelate（Cat No.:I015564）is the mandelate salt form of fesoterodine, a muscarinic receptor antagonist used in the management of overactive bladder. As a prodrug, it is rapidly hydrolyzed to 5-hydroxymethyl tolterodine, its active metabolite, which non-selectively blocks muscarinic receptors in the bladder detrusor muscle. This reduces involuntary contractions, improving symptoms of urinary urgency, frequency, and incontinence. The L-mandelate salt enhances stability and handling for pharmaceutical development. It is a valuable compound in urological research and therapeutic studies addressing bladder dysfunction and related urinary disorders.