Fasudil - CAS 103745-39-7
Fasudil (CAT: I000221), also known as Fasudil hydrochloride or HA-1077, is a potent inhibitor of multiple enzymes including ROCK-II (Rho-associated protein kinase II), PKA (protein kinase A), PKG (protein kinase G), PKC (protein kinase C), and MLCK (myosin light-chain kinase). By inhibiting these enzymes, Fasudil modulates various cellular signaling pathways involved in smooth muscle contraction, vasodilation, and cell migration. It has been studied for its therapeutic potential in conditions such as hypertension, cerebral vasospasm, and certain cardiovascular diseases.
* For research use only. Not for human or veterinary use.
|Solubility||DMSO 5 mg/mL; Water 65 mg/mL|
|Storage||Store at -20C|
|IC50||0.33 μM(for ROCK-II)|