Fasudil - CAS 103745-39-7

Fasudil (CAT: I000221), also known as Fasudil hydrochloride or HA-1077, is a potent inhibitor of multiple enzymes including ROCK-II (Rho-associated protein kinase II), PKA (protein kinase A), PKG (protein kinase G), PKC (protein kinase C), and MLCK (myosin light-chain kinase). By inhibiting these enzymes, Fasudil modulates various cellular signaling pathways involved in smooth muscle contraction, vasodilation, and cell migration. It has been studied for its therapeutic potential in conditions such as hypertension, cerebral vasospasm, and certain cardiovascular diseases.

Catalog Number: I000221

CAS Number: 103745-39-7

PubChem Substance ID:355039692

Molecular Formula: C14H17N3O2S

Molecular Weight:291.37

Purity: ≥95%

* For research use only. Not for human or veterinary use.




Molecular Formula: C14H17N3O2S
Molecular Weight291.37
SolubilityDMSO 5 mg/mL; Water 65 mg/mL
StorageStore at -20C
IC500.33 μM(for ROCK-II)