For research use only. Not for therapeutic Use.
FAK-IN-10(CAT: I040589) is a potent and selective inhibitor of focal adhesion kinase (FAK), a non-receptor tyrosine kinase implicated in tumor progression, metastasis, and resistance to therapy. By targeting the kinase activity of FAK, FAK-IN-10 disrupts integrin-mediated signaling pathways that regulate cell adhesion, migration, and survival. It has demonstrated strong anti-proliferative effects in preclinical cancer models, particularly in solid tumors with elevated FAK expression. FAK-IN-10 is a valuable tool for investigating the role of FAK in oncogenic signaling, tumor microenvironment modulation, and therapeutic resistance. Its specificity and efficacy make it suitable for use in cancer biology and targeted drug development studies.
| CAS Number | 491839-65-7 |
| Synonyms | 1-(4-bromophenyl)-2-[(5-pyridin-4-yl-1,3,4-oxadiazol-2-yl)sulfanyl]ethanone |
| Molecular Formula | C15H10BrN3O2S |
| Purity | ≥95% |
| IUPAC Name | 1-(4-bromophenyl)-2-[(5-pyridin-4-yl-1,3,4-oxadiazol-2-yl)sulfanyl]ethanone |
| InChI | InChI=1S/C15H10BrN3O2S/c16-12-3-1-10(2-4-12)13(20)9-22-15-19-18-14(21-15)11-5-7-17-8-6-11/h1-8H,9H2 |
| InChIKey | RZRDLDDOZNGXJT-UHFFFAOYSA-N |
| SMILES | C1=CC(=CC=C1C(=O)CSC2=NN=C(O2)C3=CC=NC=C3)Br |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
