Euphorbiasteroid

• CAT Number: I018253
• CAS Number: 28649-59-4
• Molecular Formula: C32H40O8
• Molecular Weight: 552.66
• Purity: ≥95%
• Storage: 3 years-20°Cpowder
• SMILES: CC1CC2(C(C1OC(=O)CC3=CC=CC=C3)C(C4(CCC5C(C5(C)C)C=C(C2=O)C)CO4)OC(=O)C)OC(=O)C

Euphorbiasteroid (Euphorbia factor L1), a component of Euphorbia lathyris L., inhibits adipogenesis of 3T3-L1 cells through activation of the AMPK pathway and induces HL-60 cells to apoptosis via promoting Bcl-2/Bax apoptotic signaling pathway in a dose-dependent manner. Euphorbiasteroid is a tricyclic diperpene of Euphorbia lathyris L., inhibits tyrosinase, and increases the phosphorylation of AMPK, with anti-cancer, anti-virus, anti-obesity and multidrug resistance-modulating effect.

Reference

[1] Park SJ, et al. Cell Biochem Funct. 2015, 33(4):220-5.
[2] Jung Sook Choi, et al. Phytotherapy research. 2010, 24(7):1042-1046.