For research use only. Not for therapeutic Use.
Eupalinolide B（Cat No.:R025322）is a sesquiterpene lactone isolated from Eupatorium species, recognized for its potent bioactivities. It exhibits strong anticancer properties by inhibiting tumor cell proliferation, inducing apoptosis, and disrupting key signaling pathways such as STAT3 and NF-κB. Eupalinolide B also shows anti-inflammatory effects, reducing pro-inflammatory mediators and modulating oxidative stress responses. Preliminary studies suggest its potential in suppressing angiogenesis and metastasis, highlighting its promise as a natural therapeutic candidate. Its diverse pharmacological profile makes it valuable in cancer, inflammation, and immunology research.
| CAS Number | 877822-41-8 |
| Synonyms | [(3aR,4R,6Z,9S,10E,11aR)-9-acetyloxy-6-(acetyloxymethyl)-10-methyl-3-methylidene-2-oxo-3a,4,5,8,9,11a-hexahydrocyclodeca[b]furan-4-yl] (E)-4-hydroxy-2-methylbut-2-enoate |
| Molecular Formula | C24H30O9 |
| Purity | ≥95% |
| IUPAC Name | [(3aR,4R,6Z,9S,10E,11aR)-9-acetyloxy-6-(acetyloxymethyl)-10-methyl-3-methylidene-2-oxo-3a,4,5,8,9,11a-hexahydrocyclodeca[b]furan-4-yl] (E)-4-hydroxy-2-methylbut-2-enoate |
| InChI | InChI=1S/C24H30O9/c1-13(8-9-25)23(28)32-21-11-18(12-30-16(4)26)6-7-19(31-17(5)27)14(2)10-20-22(21)15(3)24(29)33-20/h6,8,10,19-22,25H,3,7,9,11-12H2,1-2,4-5H3/b13-8+,14-10+,18-6-/t19-,20+,21+,22-/m0/s1 |
| InChIKey | HPWMABTYJYZFLK-FHEQDPKSSA-N |
| SMILES | C/C/1=C\[C@@H]2[C@@H]([C@@H](C/C(=C/C[C@@H]1OC(=O)C)/COC(=O)C)OC(=O)/C(=C/CO)/C)C(=C)C(=O)O2 |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
