Have any questions?
+1-862-686-3898
CAS No.: 1206123-37-6
Inquire Etrasimod (cas: 1206123-37-6 ) online by filling out the inquiry form, we will get back to you within 24 hours!
| Product Details | |
|---|---|
For research use only. Not Intended for Therapeutic Use! |
|
| Cat No: | I006736 |
| Synonyms: | APD334; APD-334; APD 334; Etrasimod.;(R)-2-(7-((4-cyclopentyl-3-(trifluoromethyl)benzyl)oxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid |
| Molecular Formula: | C26H26F3NO3 |
| Molecular Weight: | 457.5 |
| Description: | Etrasimod, also known as APD334, is a potent, centrally available, functional antagonists of the S1P1 receptor for use as next generation therapeutics for treating multiple sclerosis (MS) and other autoimmune diseases. APD334 has a favorable PK/PD profile, producing robust lymphocyte lowering at relatively low plasma concentrations in several preclinical species. APD334 was efficacious in a mouse experimental autoimmune encephalomyelitis (EAE) model of MS and a rat collagen induced arthritis (CIA) model and was found to have appreciable central exposure. |
| Price: | Get quote |
We would like to match the lowest price on market if possible.
Etrasimod, also known as APD334, is a potent, centrally available, functional antagonists of the S1P1 receptor for use as next generation therapeutics for treating multiple sclerosis (MS) and other autoimmune diseases. APD334 has a favorable PK/PD profile, producing robust lymphocyte lowering at relatively low plasma concentrations in several preclinical species. APD334 was efficacious in a mouse experimental autoimmune encephalomyelitis (EAE) model of MS and a rat collagen induced arthritis (CIA) model and was found to have appreciable central exposure.
Your information is safe with us.