Ethyl 5-(benzyloxy)-1H-indole-2-carboxylate

• CAT Number: L042937
• CAS Number: 37033-95-7
• Molecular Formula: C18H17NO3
• Molecular Weight: 295.30
• Purity: ≥95%
• IUPAC Name: ethyl 5-phenylmethoxy-1H-indole-2-carboxylate
• InChI: InChI=1S/C18H17NO3/c1-2-21-18(20)17-11-14-10-15(8-9-16(14)19-17)22-12-13-6-4-3-5-7-13/h3-11,19H,2,12H2,1H3
• InChIKey: DCIFXYFKVKDOLL-UHFFFAOYSA-N
• SMILES: CCOC(=O)C1=CC2=C(N1)C=CC(=C2)OCC3=CC=CC=C3

Ethyl 5-(benzyloxy)-1H-indole-2-carboxylate（Cat No.:L042937）is an indole-based ester featuring a benzyloxy group at the 5-position and an ethyl ester at the 2-position of the indole ring. This compound is commonly used as an intermediate in the synthesis of pharmaceuticals and biologically active molecules, especially those targeting serotonin receptors or kinases. The benzyloxy substituent enhances lipophilicity and can be removed via hydrogenolysis, offering synthetic flexibility. The ethyl ester allows for further derivatization, such as hydrolysis or amidation. Its indole core makes it valuable in medicinal chemistry and heterocyclic compound development.