Ethyl 3-Aminocrotonate

• CAT Number: R061059
• CAS Number: 7318-00-5
• Molecular Formula: C₆H₁₁NO₂
• Molecular Weight: 129.16
• Purity: ≥95%
• Synonyms: 3-Amino-2-butenoic Acid Ethyl Ester; β-Aminocrotonic Acid Ethyl Ester; 3-Aminocrotonic Acid Ethyl Ester; Ethyl 3-Amino-2-butenoate; Ethyl β-Amino-β-methylacrylate; Ethyl β-Aminocrotonate; NSC 1086; β-Aminocrotonic Acid Ethyl Ester
• Storage: -20°C
• IUPAC Name: ethyl 3-aminobut-2-enoate
• InChI: InChI=1S/C6H11NO2/c1-3-9-6(8)4-5(2)7/h4H,3,7H2,1-2H3
• InChIKey: YPMPTULBFPFSEQ-UHFFFAOYSA-N
• SMILES: CCOC(=O)C=C(C)N

Ethyl 3-aminocrotonate(CAT: R061059) is a multifunctional enamine ester widely used as a key intermediate in organic and pharmaceutical synthesis. Featuring both an amino group and an α,β-unsaturated ester moiety, it exhibits high reactivity in Michael additions, cyclizations, and heterocycle formation. This compound is especially valuable in the synthesis of pyridines, pyrazoles, and other nitrogen-containing heterocycles commonly found in bioactive molecules and drug candidates. Its stability, solubility in organic solvents, and ease of derivatization make ethyl 3-aminocrotonate a go-to building block for medicinal chemists and synthetic researchers working to develop advanced materials and therapeutic agents.