Ethyl 2-(2,4,5-trimethoxybenzamido)thiazole-4-carboxylate

• CAT Number: L018537
• CAS Number: 185105-98-0
• Molecular Formula: C16H18N2O6S
• Molecular Weight: 366.41
• Purity: ≥95%
• IUPAC Name: ethyl 2-[(2,4,5-trimethoxybenzoyl)amino]-1,3-thiazole-4-carboxylate
• InChI: InChI=1S/C16H18N2O6S/c1-5-24-15(20)10-8-25-16(17-10)18-14(19)9-6-12(22-3)13(23-4)7-11(9)21-2/h6-8H,5H2,1-4H3,(H,17,18,19)
• InChIKey: BWDNVLPYCMAUGL-UHFFFAOYSA-N
• SMILES: CCOC(=O)C1=CSC(=N1)NC(=O)C2=CC(=C(C=C2OC)OC)OC

Ethyl 2-(2,4,5-trimethoxybenzamido)thiazole-4-carboxylate(CAT: L018537) is a bioactive heterocyclic compound featuring a thiazole ring substituted with a carboxylic acid ester and an amide-linked 2,4,5-trimethoxybenzene moiety. This structure is characteristic of pharmacologically relevant scaffolds, often explored in anticancer, anti-inflammatory, and enzyme-inhibitor research. The trimethoxybenzene group enhances membrane permeability and target affinity, while the thiazole core supports metabolic stability. It is frequently used in structure–activity relationship (SAR) studies, medicinal chemistry programs, and the synthesis of small-molecule libraries. This compound offers versatility for drug discovery efforts targeting kinases, G-protein coupled receptors (GPCRs), or epigenetic enzymes.