Erythrosine B

• CAT Number: R042366
• CAS Number: 16423-68-0
• Molecular Formula: C20H6I4Na2O5
• Molecular Weight: 879.86
• Purity: ≥95%
• Synonyms: 3’,6’-Dihydroxy-2’,4’,5’,7’-tetraiodo-spiro[isobenzofuran-1(3H),9’-[9H]xanthen]-3-one; rythrosine B (6CI); Fluorescein, 2’,4’,5’,7’-tetraiodo-, disodium salt (8CI); 1427 Red; 1671 Red; 2,4,5,7-Tetraiodofluorescein Disodium Salt; 2’,4’,5’,7’-Tetraiodo
• Storage: Store at RT
• IUPAC Name: disodium;2',4',5',7'-tetraiodo-3-oxospiro[2-benzofuran-1,9'-xanthene]-3',6'-diolate
• InChI: InChI=1S/C20H8I4O5.2Na/c21-11-5-9-17(13(23)15(11)25)28-18-10(6-12(22)16(26)14(18)24)20(9)8-4-2-1-3-7(8)19(27)29-20;;/h1-6,25-26H;;/q;2*+1/p-2
• InChIKey: RAGZEDHHTPQLAI-UHFFFAOYSA-L
• SMILES: C1=CC=C2C(=C1)C(=O)OC23C4=CC(=C(C(=C4OC5=C(C(=C(C=C35)I)[O-])I)I)[O-])I.[Na+].[Na+]

Erythrosine B（Cat No.:R042366）, also known as Red No. 3, is a synthetic red dye derived from fluorone, characterized by its bright pink to red color. It is commonly used as a coloring agent in food, pharmaceuticals, and cosmetics. Chemically, it is a tetraiodofluorescein sodium salt, giving it high water solubility and intense fluorescence. In biological research, Erythrosine B serves as a photosensitizer and a tracer dye. While approved for limited use in some countries, its application is regulated due to concerns over potential health effects with excessive or prolonged exposure.

Reference

1.Merzlyak, Ekaterina M., et al. "Bright monomeric red fluorescent protein with an extended fluorescence lifetime." Nature methods 4.7 (2007): 555-557.
2.Lafferman, Jeffrey A., and Ellen K. Silbergeld. "Erythrosin B inhibits dopamine transport in rat caudate synaptosomes." Science 205.4404 (1979): 410-412.
3.Silbergeld, Ellen K. "Erythrosin B is a specific inhibitor of high affinity 3H-ouabain binding and ion transport in rat brain." Neuropharmacology 20.1 (1981): 87-90.