For research use only. Not for therapeutic Use.
ER176（Cat No.:R072267）is a high-affinity positron emission tomography (PET) radioligand targeting the 18 kDa translocator protein (TSPO), a biomarker of neuroinflammation and microglial activation. Designed for improved binding specificity and signal-to-noise ratio, ER176 enables precise imaging of TSPO expression in the brain, even in individuals with varying TSPO binding affinity genotypes. Its enhanced pharmacokinetic properties make it valuable for research in neurodegenerative diseases, psychiatric disorders, and brain injury. ER176 facilitates the in vivo study of neuroinflammatory processes, aiding in diagnosis, disease monitoring, and the evaluation of anti-inflammatory therapeutic interventions in the central nervous system.
| CAS Number | 1373887-29-6 |
| Synonyms | N-[(2R)-butan-2-yl]-4-(2-chlorophenyl)-N-methylquinazoline-2-carboxamide |
| Molecular Formula | C20H20ClN3O |
| Purity | ≥95% |
| IUPAC Name | N-[(2R)-butan-2-yl]-4-(2-chlorophenyl)-N-methylquinazoline-2-carboxamide |
| InChI | InChI=1S/C20H20ClN3O/c1-4-13(2)24(3)20(25)19-22-17-12-8-6-10-15(17)18(23-19)14-9-5-7-11-16(14)21/h5-13H,4H2,1-3H3/t13-/m1/s1 |
| InChIKey | ASFLYNMYGAYKON-CYBMUJFWSA-N |
| SMILES | CC[C@@H](C)N(C)C(=O)C1=NC2=CC=CC=C2C(=N1)C3=CC=CC=C3Cl |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
