Epsilon-(gamma-glutamyl)-lysine TFA

• CAT Number: I044177
• Molecular Formula: C13H22F3N3O7
• Molecular Weight: 389.32
• Purity: ≥95%
• Synonyms: (2S)-2-amino-6-[[(4S)-4-amino-4-carboxybutanoyl]amino]hexanoic acid;2,2,2-trifluoroacetic acid
• IUPAC Name: (2S)-2-amino-6-[[(4S)-4-amino-4-carboxybutanoyl]amino]hexanoic acid
• InChI: InChI=1S/C11H21N3O5/c12-7(10(16)17)3-1-2-6-14-9(15)5-4-8(13)11(18)19/h7-8H,1-6,12-13H2,(H,14,15)(H,16,17)(H,18,19)/t7-,8-/m0/s1
• InChIKey: JPKNLFVGUZRHOB-YUMQZZPRSA-N
• SMILES: C(CCNC(=O)CC[C@@H](C(=O)O)N)C[C@@H](C(=O)O)N

Epsilon-(γ-Glutamyl)-lysine TFA（Cat No.:I044177）is a synthetic dipeptide that mimics the natural isopeptide bond formed by transglutaminase enzymes between glutamine and lysine residues in proteins. This compound serves as a model substrate or inhibitor in studies of transglutaminase activity, protein crosslinking, and post-translational modifications. It is commonly used in biochemical assays to investigate the role of ε-(γ-glutamyl)-lysine linkages in tissue stabilization, wound healing, and neurodegenerative diseases. The trifluoroacetate (TFA) salt form enhances solubility and handling in aqueous environments, making it ideal for laboratory and enzymology applications.