Epimagnolin A

• CAT Number: I044934
• CAS Number: 41689-51-4
• Molecular Formula: C23H28O7
• Molecular Weight: 416.46
• Purity: ≥95%
• Synonyms: (3S,3aR,6R,6aR)-3-(3,4-dimethoxyphenyl)-6-(3,4,5-trimethoxyphenyl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan
• InChI: InChI=1S/C23H28O7/c1-24-17-7-6-13(8-18(17)25-2)21-15-11-30-22(16(15)12-29-21)14-9-19(26-3)23(28-5)20(10-14)27-4/h6-10,15-16,21-22H,11-12H2,1-5H3/t15-,16-,21+,22-/m0/s1
• InChIKey: MFIHSKBTNZNJIK-FRMGNDQPSA-N
• SMILES: COC1=C(C=C(C=C1)[C@@H]2[C@H]3CO[C@H]([C@H]3CO2)C4=CC(=C(C(=C4)OC)OC)OC)OC

Epimagnolin A（Cat No.:I044934）is a bioactive lignan compound isolated from the flower buds of Magnolia species, particularly Magnolia fargesii, used in traditional East Asian medicine. It features a dioxabicyclo[3.3.0]octane core and exhibits various pharmacological effects, including anti-inflammatory, analgesic, and neuroprotective properties. Epimagnolin A is known to inhibit pro-inflammatory cytokines and modulate key signaling pathways such as NF-κB and MAPK. It has been investigated for its potential in treating conditions like allergic rhinitis, neurodegenerative disorders, and oxidative stress-related diseases. Its presence enhances the therapeutic value of Magnolia-based herbal formulations.