For research use only. Not for therapeutic Use.
EPI-589(CAT: I017136) is a quinone derivative and potent oxidoreductase enzyme inhibitor with promising therapeutic potential in neurodegenerative diseases. Preclinical and clinical studies highlight its safety, tolerability, and ability to modulate redox balance in neuronal tissues. EPI-589 has shown efficacy in models of amyotrophic lateral sclerosis (ALS), where it improves cerebrospinal fluid (CSF) and plasma biomarkers linked to neuroinflammation and disease progression. By targeting oxidative stress pathways, EPI-589 supports neuronal survival and function, making it an important tool for research into ALS and related neurodegenerative disorders. Its unique mechanism positions it as a candidate for disease-modifying therapy.
| CAS Number | 1147883-03-1 |
| Synonyms | (2R)-2-hydroxy-2-methyl-4-(2,4,5-trimethyl-3,6-dioxocyclohexa-1,4-dien-1-yl)butanamide |
| Molecular Formula | C14H19NO4 |
| Purity | ≥95% |
| IUPAC Name | (2R)-2-hydroxy-2-methyl-4-(2,4,5-trimethyl-3,6-dioxocyclohexa-1,4-dien-1-yl)butanamide |
| InChI | InChI=1S/C14H19NO4/c1-7-8(2)12(17)10(9(3)11(7)16)5-6-14(4,19)13(15)18/h19H,5-6H2,1-4H3,(H2,15,18)/t14-/m1/s1 |
| InChIKey | BAANPNDZFYBQIB-CQSZACIVSA-N |
| SMILES | CC1=C(C(=O)C(=C(C1=O)C)CCC(C)(C(=O)N)O)C |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |