For research use only. Not for therapeutic Use.
ENMD-1068 hydrochloride（Cat No.:I045834）is a small-molecule antagonist of protease-activated receptor-2 (PAR-2), a G-protein-coupled receptor implicated in inflammation, pain signaling, and cancer progression. By blocking PAR-2 activation, ENMD-1068 hydrochloride reduces pro-inflammatory cytokine release, nociceptive responses, and tumor-promoting pathways. It has been widely used in preclinical studies to investigate mechanisms of inflammatory diseases, arthritis, neuropathic pain, and cancer biology. The hydrochloride salt form enhances solubility and experimental utility, making it a reliable pharmacological tool for probing PAR-2 function and assessing therapeutic strategies targeting inflammation and tumor microenvironment modulation.
| CAS Number | 2703451-51-6 |
| Synonyms | 6-amino-1-[4-(3-methylbutanoyl)piperazin-1-yl]hexan-1-one;hydrochloride |
| Molecular Formula | C15H30ClN3O2 |
| Purity | ≥95% |
| IUPAC Name | 6-amino-1-[4-(3-methylbutanoyl)piperazin-1-yl]hexan-1-one;hydrochloride |
| InChI | InChI=1S/C15H29N3O2.ClH/c1-13(2)12-15(20)18-10-8-17(9-11-18)14(19)6-4-3-5-7-16;/h13H,3-12,16H2,1-2H3;1H |
| InChIKey | UDMQQSSIEIJEHG-UHFFFAOYSA-N |
| SMILES | CC(C)CC(=O)N1CCN(CC1)C(=O)CCCCCN.Cl |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
