Endothall

• CAT Number: R033210
• CAS Number: 145-73-3
• Molecular Formula: C8H10O5
• Molecular Weight: 186.16
• Purity: ≥95%
• Synonyms: 7-oxabicyclo[2.2.1]heptane-2,3-dicarboxylic acid
• InChI: InChI=1S/C8H10O5/c9-7(10)5-3-1-2-4(13-3)6(5)8(11)12/h3-6H,1-2H2,(H,9,10)(H,11,12)
• InChIKey: GXEKYRXVRROBEV-UHFFFAOYSA-N
• SMILES: C1CC2C(C(C1O2)C(=O)O)C(=O)O

Endothall (Cat No.: R033210) is a contact herbicide and defoliant widely used for the control of aquatic weeds, terrestrial broadleaf weeds, and algae. It acts as a protein phosphatase inhibitor, disrupting cellular metabolism, growth, and membrane integrity, leading to rapid plant death. Endothall is applied in agriculture, aquatics, and turf management, particularly for invasive weed control in irrigation canals, lakes, and reservoirs. In research, it serves as a biochemical probe for studying phosphatase-regulated signaling pathways, apoptosis, and cell cycle progression in plants and animals.

Reference

[1]. Janetti R Signorelli, et al. Protein phosphatases decrease their activity during capacitation: a new requirement for this event. PLoS One. 2013 Dec 2;8(12):e81286.
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[2]. J P Thièry, et al. Hepatocellular carcinoma cell lines from diethylnitrosamine phenobarbital-treated rats. Characterization and sensitivity to endothall, a protein serine/threonine phosphatase-2A inhibitor. Hepatology. 1999 May;29(5):1406-17.
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