For research use only. Not for therapeutic Use.
endo-BCN-PEG2-NH2（Cat No.:I044737）is a heterobifunctional linker featuring a strained alkyne (endo-BCN, bicyclo[6.1.0]non-4-yne) group, a short PEG2 (diethylene glycol) spacer, and a terminal amine. The BCN group enables copper-free strain-promoted azide-alkyne cycloaddition (SPAAC), allowing fast, biocompatible click chemistry with azide-containing molecules. The primary amine provides a reactive site for conjugation to carboxylic acids or activated esters. The PEG2 spacer enhances solubility, flexibility, and reduces steric hindrance. endo-BCN-PEG2-NH2 is ideal for bioorthogonal labeling, drug delivery, and biomolecular conjugation in living systems, enabling selective and efficient bioconjugation without metal catalysts.
| CAS Number | 1263166-93-3 |
| Molecular Formula | C17H28N2O4 |
| Purity | ≥95% |
| IUPAC Name | [(1S,8R)-9-bicyclo[6.1.0]non-4-ynyl]methyl N-[2-[2-(2-aminoethoxy)ethoxy]ethyl]carbamate |
| InChI | InChI=1S/C17H28N2O4/c18-7-9-21-11-12-22-10-8-19-17(20)23-13-16-14-5-3-1-2-4-6-15(14)16/h14-16H,3-13,18H2,(H,19,20)/t14-,15+,16? |
| InChIKey | YZGOWXGENSKDSE-XYPWUTKMSA-N |
| SMILES | C1C[C@@H]2[C@@H](C2COC(=O)NCCOCCOCCN)CCC#C1 |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
