endo-BCN-PEG2-alcohol

• CAT Number: I014356
• CAS Number: 1807501-85-4
• Molecular Formula: C17H27NO5
• Molecular Weight: 325.40
• Purity: ≥95%
• Synonyms: 9-bicyclo[6.1.0]non-4-ynylmethyl N-[2-[2-(2-hydroxyethoxy)ethoxy]ethyl]carbamate
• InChI: InChI=1S/C17H27NO5/c19-8-10-22-12-11-21-9-7-18-17(20)23-13-16-14-5-3-1-2-4-6-15(14)16/h14-16,19H,3-13H2,(H,18,20)
• InChIKey: PEXDOIHAKXYTET-UHFFFAOYSA-N
• SMILES: C1CC2C(C2COC(=O)NCCOCCOCCO)CCC#C1

endo-BCN-PEG2-alcohol（Cat No.:I014356）is a hydrophilic, multifunctional linker optimized for bioorthogonal conjugation. It features an endo-bicyclononyne (endo-BCN) group that enables strain-promoted azide–alkyne cycloaddition (SPAAC), offering copper-free click chemistry with high selectivity and efficiency under mild conditions. The PEG2 spacer improves solubility, provides flexibility, and reduces steric hindrance, ensuring compatibility with biomolecules and polymers. The terminal hydroxyl group offers an additional handle for further derivatization or coupling. This reagent is widely applied in chemical biology, drug delivery, diagnostic probe development, and polymer–biomolecule conjugation, where clean, biocompatible click chemistry is essential.