Enapotamab

• CAT Number: I042232
• CAS Number: 1912423-61-0
• Purity: ≥95%

Enapotamab (Cat No.: I042232) is a human monoclonal antibody that targets AXL, a receptor tyrosine kinase involved in tumor growth, metastasis, and resistance to therapy. By binding to AXL, enapotamab blocks its signaling pathways, promoting cancer cell apoptosis and inhibiting tumor progression. It has shown potential in treating various solid tumors, including non-small cell lung cancer and sarcomas. Enapotamab is also used in the development of antibody-drug conjugates (ADCs) to enhance specificity and efficacy, making it a promising candidate in targeted cancer therapy.

Reference

[1]. Matthew T. Burger, et al. Bcl-xl inhibitor antibody-drug conjugates and methods of use thereof. WO2022115477A1.