Empasiprubart

• CAT Number: I040391
• CAS Number: 2579031-19-7
• Purity: ≥95%

Empasiprubart(CAT: I040391) is a humanized IgG1κ monoclonal antibody designed to target CD47, a key “don’t eat me” signal overexpressed on many tumor cells. By binding CD47 and blocking its interaction with SIRPα on macrophages, Empasiprubart promotes phagocytosis of cancer cells while sparing normal cells. It is currently under investigation in clinical trials (Phase I/II) for solid tumors and hematologic malignancies. Preclinical studies demonstrate enhanced tumor clearance, immune activation, and synergy with checkpoint inhibitors and antibody–drug conjugates. Supplied at high purity, Empasiprubart is ideal for research in tumor immunology, macrophage-targeted therapies, and combination immuno-oncology strategies.