For research use only. Not for therapeutic Use.
Emlenoflast sodium（Cat No.:I044678）is a selective cathepsin K inhibitor developed for the treatment of osteoporosis and other bone-resorptive disorders. Cathepsin K is a protease highly expressed in osteoclasts, playing a key role in the degradation of bone matrix proteins such as collagen. By inhibiting this enzyme, emlenoflast sodium reduces excessive bone resorption while preserving bone formation, offering a balanced approach to improving bone density and strength. It has shown promise in preclinical and clinical studies, potentially serving as a therapeutic option for postmenopausal osteoporosis and related skeletal conditions with fewer side effects than traditional therapies.
| CAS Number | 2380032-29-9 |
| Synonyms | sodium;1,2,3,5,6,7-hexahydro-s-indacen-4-ylcarbamoyl-(1-propan-2-ylpyrazol-3-yl)sulfonylazanide |
| Molecular Formula | C19H23N4NaO3S |
| Purity | ≥95% |
| IUPAC Name | sodium;1,2,3,5,6,7-hexahydro-s-indacen-4-ylcarbamoyl-(1-propan-2-ylpyrazol-3-yl)sulfonylazanide |
| InChI | InChI=1S/C19H24N4O3S.Na/c1-12(2)23-10-9-17(21-23)27(25,26)22-19(24)20-18-15-7-3-5-13(15)11-14-6-4-8-16(14)18;/h9-12H,3-8H2,1-2H3,(H2,20,22,24);/q;+1/p-1 |
| InChIKey | RKEFKQUKINZXDR-UHFFFAOYSA-M |
| SMILES | CC(C)N1C=CC(=N1)S(=O)(=O)[N-]C(=O)NC2=C3CCCC3=CC4=C2CCC4.[Na+] |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
