For research use only. Not for therapeutic Use.
Emlenoflast（Cat No.:I026828）is a selective, orally active inhibitor of cathepsin K, an enzyme critical for bone matrix degradation by osteoclasts. By blocking cathepsin K, emlenoflast reduces bone resorption without significantly impairing bone formation, offering a novel mechanism for treating osteoporosis and other bone-related disorders. It has demonstrated potential in increasing bone mineral density and improving bone quality in preclinical and clinical studies. Emlenoflast aims to provide an alternative to traditional anti-resorptive therapies, with a favorable safety profile and the potential to preserve bone remodeling balance in patients with skeletal fragility.
| CAS Number | 1995067-59-8 |
| Synonyms | 1-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)-3-(1-propan-2-ylpyrazol-3-yl)sulfonylurea |
| Molecular Formula | C19H24N4O3S |
| Purity | ≥95% |
| IUPAC Name | 1-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)-3-(1-propan-2-ylpyrazol-3-yl)sulfonylurea |
| InChI | InChI=1S/C19H24N4O3S/c1-12(2)23-10-9-17(21-23)27(25,26)22-19(24)20-18-15-7-3-5-13(15)11-14-6-4-8-16(14)18/h9-12H,3-8H2,1-2H3,(H2,20,22,24) |
| InChIKey | MTOUOUSKXWSTAX-UHFFFAOYSA-N |
| SMILES | CC(C)N1C=CC(=N1)S(=O)(=O)NC(=O)NC2=C3CCCC3=CC4=C2CCC4 |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
