Emideltide

• CAT Number: I014352
• CAS Number: 62568-57-4
• Molecular Formula: C35H48N10O15
• Molecular Weight: 848.82
• Purity: ≥95%
• Solubility: Soluble in DMSO
• IUPAC Name: (2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-[[(2S)-2-amino-3-(1H-indol-3-yl)propanoyl]amino]propanoyl]amino]acetyl]amino]acetyl]amino]-3-carboxypropanoyl]amino]propanoyl]amino]-3-hydroxypropanoyl]amino]acetyl]amino]pentanedioic acid
• InChI: InChI=1S/C35H48N10O15/c1-16(41-32(56)20(36)9-18-11-37-21-6-4-3-5-19(18)21)30(54)39-12-25(47)38-13-26(48)44-23(10-29(52)53)34(58)42-17(2)31(55)45-24(15-46)33(57)40-14-27(49)43-22(35(59)60)7-8-28(50)51/h3-6,11,16-17,20,22-24,37,46H,7-10,12-15,36H2,1-2H3,(H,38,47)(H,39,54)(H,40,57)(H,41,56)(H,42,58)(H,43,49)(H,44,48)(H,45,55)(H,50,51)(H,52,53)(H,59,60)/t16-,17-,20-,22-,23-,24-/m0/s1
• InChIKey: ZRZROXNBKJAOKB-GFVHOAGBSA-N
• SMILES: O=C(O)CC[C@@H](C(O)=O)NC(CNC([C@H](CO)NC([C@H](C)NC([C@H](CC(O)=O)NC(CNC(CNC([C@H](C)NC([C@H](CC1=CNC2=C1C=CC=C2)N)=O)=O)=O)=O)=O)=O)=O)=O

Emideltide (CAS 62568-57-4) promotes sleep by targeting various areas of the brain. The peptide is easily absorbed from the gut and is not denatured by enzymes. It crosses the blood-brain barrier easily. It influences the circadian rhythm in humans. Low concentrations of the peptide are observed in patients with schizophrenia and depression.

Reference

1.Pollard, B. J., and C. J. D. Pomfrett. "Delta sleep-inducing peptide." European journal of anaesthesiology 18.7 (2001): 419-422.