For research use only. Not for therapeutic Use.
Emedastine(CAT: I016686) is a selective, second-generation histamine H₁ receptor antagonist used primarily in allergy research. By blocking H₁ receptors, it prevents histamine-mediated responses such as vasodilation, vascular permeability, and pruritus. Unlike first-generation antihistamines, Emedastine demonstrates minimal penetration of the blood–brain barrier, reducing sedative side effects. It has been widely investigated for its efficacy in treating allergic conjunctivitis and other hypersensitivity conditions. Emedastine is a valuable tool for studying histamine receptor pharmacology, allergy mechanisms, and therapeutic approaches for ocular and systemic allergic disorders, supporting both pharmacological studies and translational allergy research.
| CAS Number | 87233-61-2 |
| Synonyms | 1-(2-ethoxyethyl)-2-(4-methyl-1,4-diazepan-1-yl)benzimidazole |
| Molecular Formula | C17H26N4O |
| Purity | ≥95% |
| IUPAC Name | 1-(2-ethoxyethyl)-2-(4-methyl-1,4-diazepan-1-yl)benzimidazole |
| InChI | InChI=1S/C17H26N4O/c1-3-22-14-13-21-16-8-5-4-7-15(16)18-17(21)20-10-6-9-19(2)11-12-20/h4-5,7-8H,3,6,9-14H2,1-2H3 |
| InChIKey | KBUZBQVCBVDWKX-UHFFFAOYSA-N |
| SMILES | CCOCCN1C2=CC=CC=C2N=C1N3CCCN(CC3)C |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
