For research use only. Not for therapeutic Use.
EMAC10101d（Cat No.:I026809）is a potent, selective small-molecule inhibitor of human carbonic anhydrase II (hCA II), displaying a Ki of just 8.1 nM, making it effective at low nanomolar concentrations. Structurally, it features a dihydrothiazole core substituted at position 4 with a 2,4-dichlorophenyl moiety and a benzenesulfonamide group, which confers high isoform specificity. Its molecular formula is C₁₇H₁₅Cl₂N₃O₂S₂, with a molecular weight of 428.36 g/mol. Supplied as a high‑purity solid (≥99.7%), it dissolves well in DMSO and is used mainly for biochemical assays, structural studies, and drug discovery targeting CA-related diseases.
| CAS Number | 2561476-24-0 |
| Synonyms | 4-[[4-(2,4-dichlorophenyl)-3-ethyl-1,3-thiazol-2-ylidene]amino]benzenesulfonamide |
| Molecular Formula | C17H15Cl2N3O2S2 |
| Purity | ≥95% |
| IUPAC Name | 4-[[4-(2,4-dichlorophenyl)-3-ethyl-1,3-thiazol-2-ylidene]amino]benzenesulfonamide |
| InChI | InChI=1S/C17H15Cl2N3O2S2/c1-2-22-16(14-8-3-11(18)9-15(14)19)10-25-17(22)21-12-4-6-13(7-5-12)26(20,23)24/h3-10H,2H2,1H3,(H2,20,23,24) |
| InChIKey | OEGLVUQKHJHUEU-UHFFFAOYSA-N |
| SMILES | CCN1C(=CSC1=NC2=CC=C(C=C2)S(=O)(=O)N)C3=C(C=C(C=C3)Cl)Cl |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
