EGTA

• CAT Number: R025686
• CAS Number: 67-42-5
• Molecular Formula: C14H24N2O10
• Molecular Weight: 380.35
• Purity: ≥95%
• Synonyms: 1,2-Bis(2-aminoethoxyethane)-N,N,N’,N’-tetraacetic Acid; 2,2’-Ethylenedioxybis(ethylamine)-N,N,N’,N’-tetraacetic Acid; 3,12-Bis(carboxymethyl)-6,9-dioxa-3,12-diazatetradecanedioic Acid; 3,6-Dioxaoctane-1,8-diamine-N,N,N’,N’-tetraacetic Acid; Chelest
• Target: Reagents
• Solubility: Soluble to 100 mM in 1M NaOH
• Storage: Store at RT
• IUPAC Name: 2-[2-[2-[2-[bis(carboxymethyl)amino]ethoxy]ethoxy]ethyl-(carboxymethyl)amino]acetic acid
• InChI: InChI=1S/C14H24N2O10/c17-11(18)7-15(8-12(19)20)1-3-25-5-6-26-4-2-16(9-13(21)22)10-14(23)24/h1-10H2,(H,17,18)(H,19,20)(H,21,22)(H,23,24)
• InChIKey: DEFVIWRASFVYLL-UHFFFAOYSA-N
• SMILES: C(COCCOCCN(CC(=O)O)CC(=O)O)N(CC(=O)O)CC(=O)O

EGTA (Cat No.:R025686) is a chelating agent structurally similar to EDTA but with a higher selectivity for calcium ions over magnesium ions. It is a white, water-soluble solid used extensively in biochemistry and molecular biology to tightly bind calcium and control calcium-dependent processes. EGTA is especially useful in studies of calcium signaling, enzymatic regulation, and buffer systems where precise control of free Ca²⁺ concentrations is critical. Its four carboxyl and two amine groups form stable complexes with divalent cations, making it essential in calcium-sensitive experimental setups.