For research use only. Not for therapeutic Use.
Efflux Inhibitor-1 (Cat No.: I042334) is a small-molecule compound designed to block the action of bacterial efflux pumps, which are membrane transport proteins that expel antibiotics and other toxic substances from bacterial cells. By inhibiting these pumps, Efflux Inhibitor-1 restores or enhances the efficacy of antimicrobial agents, particularly against multidrug-resistant (MDR) strains. It is widely used in microbiology and pharmacology research to study resistance mechanisms, evaluate drug combinations, and support the development of novel therapies to overcome bacterial antibiotic resistance.
| CAS Number | 1776055-29-8 |
| Synonyms | furan-3-yl-[4-[2-(2-methoxyphenyl)-5-phenylpyrazolo[1,5-a]pyrimidin-7-yl]piperazin-1-yl]methanone |
| Molecular Formula | C28H25N5O3 |
| Purity | ≥95% |
| InChI | InChI=1S/C28H25N5O3/c1-35-25-10-6-5-9-22(25)24-17-26-29-23(20-7-3-2-4-8-20)18-27(33(26)30-24)31-12-14-32(15-13-31)28(34)21-11-16-36-19-21/h2-11,16-19H,12-15H2,1H3 |
| InChIKey | SFNWNSAJWDYPJC-UHFFFAOYSA-N |
| SMILES | COC1=CC=CC=C1C2=NN3C(=C2)N=C(C=C3N4CCN(CC4)C(=O)C5=COC=C5)C6=CC=CC=C6 |
| Reference | [1]. Larson, et al. Selective efflux inhibitors and related pharmaceutical compositions and methods of treatment: United States, US9056111[P]. 2015-06-16. |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
