Efavaleukin alfa

• CAT Number: I040370
• CAS Number: 2049067-94-7
• Purity: ≥95%

Efavaleukin alfa(CAT: I040370) is a novel, engineered interleukin-2 (IL-2) mutein fused to an Fc domain, designed to selectively expand regulatory T cells (Tregs) without broadly activating effector T cells. This fusion protein exhibits enhanced pharmacokinetics and targeted immunomodulatory activity, making it a promising therapeutic candidate for autoimmune and inflammatory diseases such as ulcerative colitis and systemic lupus erythematosus. By promoting immune tolerance through Treg expansion, Efavaleukin alfa offers a refined approach to cytokine therapy with reduced risk of systemic immune activation. It is currently under clinical investigation and serves as a key molecule in studies of Treg-mediated immune regulation.